The lysosomal enzyme beta-hexosaminidase A, which is made up of alpha and beta polypeptides, has an abnormality caused by mutations in the gene encoding its alpha subunit.
Tay-Sachs illness is a type of mutation, right?A genetic ailment called Tay-Sachs is handed down from parents to their offspring. It happens when a child receives a defective (mutated) copy of the HEXA gene from both parents. A lack of the enzyme beta-hexosaminidase A results from the genetic mutation that causes Tay-Sachs disease.
Why is Tay-Sachs illness incurable?Medical intervention can prolong life but does not enhance neurological function. Restoring the HexA enzyme in the brain is the only method of treating Tay-Sachs. However, this is challenging since the blood-brain barrier prohibits most compounds from entering the brain.
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what are some of the responsibilities of a city manager? select all that apply.(select all that apply.)
Answer:
responsabilities of a city manager
Explanation:
Un administrador de la ciudad es responsable de las operaciones diarias de una ciudad.Esto incluye la gestión del personal, el presupuesto y la planificación, la supervisión de la infraestructura y los servicios y el mantenimiento de la seguridad pública.Un administrador de la ciudad también suele liderar el esfuerzo para atraer negocios y residentes al área. Una descripción típica del trabajo de un administrador de la ciudad puede incluir: • Administrar personal • Planificación y presupuesto • Supervisar la infraestructura y los servicios • Mantener la seguridad pública • Liderar los esfuerzos para atraer negocios y residentes del área. Las responsabilidades de un administrador municipal varían según el tamaño de la ciudad, pero generalmente incluyen liderar una organización con un presupuesto anual superior a los $100 millones.
english: A city administrator is responsible for the daily operations of a city. This includes personnel management, budget and planning, supervision of infrastructure and services, and maintenance of public safety.A city administrator also often leads the effort to attract businesses and residents to the area. A typical job description of a city manager may include: • Managing staff • Planning and budgeting • Overseeing infrastructure and services • Maintaining public safety • Leading efforts to attract businesses and area residents. The responsibilities of a city administrator vary depending on the size of the city, but usually include leading an organization with an annual budget of more than $100 million.
Do subdomains have DNS records?
A DNS record for a hostname that is part of your domain is referred to as a subdomain. Simply add the DNS record for the subdomain using our DNS record editor.
Organizational needs are the key motivation for marketers and people to use a subdomain.
If you use a single domain to host your website, host different records for other tools and services your business uses, as well as all the different records that are generally connected with a workspace under a specific name, the DNS of a domain can become quite cluttered very fast.
If two entries clash or a lookup address expires, DNS can easily break.
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What are price floors used for?
Price floors can be used for agriculture, rent control, wages etc.
A price floor is a minimum price that a product may be sold for that the government has approved, with the restriction that it may not be offered for less. These are frequently used to prevent producers of a certain commodity from charging excessively cheap rates for their wares. They are designed to guarantee that manufacturers can cover their expenses and make a profit that is reasonable.
These are employed in agricultural markets where the government may impose price ceilings on certain agricultural commodities like wheat or maize in order to shield farmers from potential price declines brought on by excess production or shifts in the global market. Furthermore, the government establishes a minimum wage as a price floor for workers in some nations. This helps to safeguard against exploitation and guarantees that workers receive a set minimum wage for their labor. As certain towns or states may set price floors for rental properties to protect tenants from unreasonably high rent costs, they can also be utilised in rent control.
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which of the following statements is the most accurate? an annual average reading of less than 4 pci/l is an acceptable level of indoor radon.an annual reading of 12 pci/l is an acceptable level of indoor radon, if one does not smoke.an annual reading of 100 pci/l would not pose a health risk as long as some abatement work was done within 5 -10 years.an annual radon reading of over 200 pci/l would indicate that immediate death is certain.
Radon is a radioactive gas that has no smell, colour or taste. Radon is produced from the natural radioactive decay of uranium, which is found in all rocks and soils. Radon can also be found in water.
What are radio active gases ?
Any one of the three radioactive inert gases (actinon, thoron, and radon) that contribute to atmospheric ionisation by the ionising action of the alpha particles that they each emit upon disintegration.
These three gases all have an atomic number of 86, making them isotopic to one another. They belong to different families of radioactive elements, but they all originate from and decay through alpha emission. They develop as salts or minerals in the spaces between soil or porous rocks that retain their respective parent atoms. They reach the surface layers through exhalation.
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bacia has produced 1,500 jars of strawberry jam, using homegrown strawberries from her farm. by concentrating her efforts on advertising and publicity, she is trying to encourage people to notice and buy her product. through her promotional activities, bacia is primarily engaging in the marketing function of
Since Bacia is concentrating her efforts on advertising and publicity, she is trying to encourage people to notice and buy her product. through her promotional activities, Bacia is primarily engaging in the marketing function of selling.
What role do purchasing and selling play in marketing?The main activity in concentration is buying, whereas the main activity in dispersion is selling. The two main stages of the marketing process—concentration and dispersion involve transportation, storage, standardization and grading, funding, and risk-taking.
Therefore, a component of marketing, selling entails getting in touch with potential clients and following up on sales leads. It's crucial for marketing experts to chase sales leads subtly because doing so enables them to develop connections with future clients.
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Is Tay-Sachs a point or frameshift mutation?
Yes Tay-Sachs is a point or frameshift mutation.
Explain frameshift mutation ?The insertion or deletion of nucleotide bases in amounts that are not multiples of three is referred to as a frameshift mutation in a gene. This is significant because a cell reads the genetic code for proteins in groups of three nucleotides. These so-called "triplet codons" each stand for one of the 20 different amino acids that go into making a protein. The entire gene sequence after the mutation will be misread if a mutation alters this regular reading frame. This may lead to the incorrect amino acids being added to the protein or the development of a codon that prevents the protein from getting longer.
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Are there price controls in a free market?
Government pricing controls are frequently necessary in a free market. They are frequently applied as a direct economic intervention strategy to regulate the price of specific goods and services, such rent, gas, and food.
One type of economically essential intervention is price controls. They are commonly used to help steer the economy in a certain direction and are meant to bring down prices for consumers. For instance, it could be considered that some restrictions are necessary to keep inflation in check. Price controls are the opposite of market forces, which result in prices set by producers based on supply and demand. Price limitations are regularly imposed on consumer essentials. Restrictions set by the government may have minimums or maximums. Price floors are the lowest prices, whereas price ceilings are often referred to as price limits.
Price controls may be put in place to ensure affordability and economic stability, but they may also have the opposite effect. Price controls have a history of resulting in problems over time, such as shortages, rationing, a drop in product quality, and the creation of underground markets to sell the price-controlled goods through unauthorised channels.
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What are 2 renewable resources?
Future prospects are bright thanks to sustainable energy sources including hydrogen, solar, and wind.
What renewable resources ?Natural resources that, after being used up, can be replenished or grown back to their original levels are known as renewable resources. Resources that are only partially renewable are those whose exploitation eventually reaches a point at which regeneration is rendered impossible.Utilizing renewable energy has both economic and environmental advantages, such as producing energy with no greenhouse gas emissions from fossil fuels and reducing some forms of air pollution. increasing energy supply diversity and decreasing reliance on imported fuels.To learn more about renewable energy refer,
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If you have a conversion term policy, then?
A term-to-permanent life insurance conversion, or “term-to-perm” conversion, allows you to extend your life insurance coverage.
One party promises to reimburse the other in exchange for a fee in the event of certain loss, damage or injury as a safeguard against financial loss. This is a risk management method primarily used to protect against the risk of potential loss.
An underwriter, insurance company, insurance company or underwriter is a company that provides insurance. A person or business that buys insurance is called the policyholder, while someone or something that is covered by the policy is called the insured.
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What is the most important goal of financial management?
The goal of financial management is to maximize shareholder wealth.
Financial management is the business function concerned with profitability, expenses, cash, and credit in order for the "organisation to have the means to carry out its objective as satisfactorily as possible," with the latter often defined as maximising the firm's value for stockholders. Financial management is the practise of handling a company's finances in such a way that it can be successful while remaining compliant with regulations. That necessitates both a high-level strategy and hands-on execution.
Most financial management plans will divide them into four elements that are widely recognised in financial management. Planning, controlling, organising and directing, and decision making are the four elements.
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Does cutting taxes help the economy?
Tax reductions give people more discretionary money, which is a simple argument in favor of the idea that they promote economic growth.
What are the benefits of tax cuts for the economy?Reduced income taxes increase consumers' purchasing power and increase aggregate demand, which in turn can increase economic growth (and possibly inflation). Income tax reductions may strengthen labor incentive structures on the supply side, boosting productivity.
Are taxes harmful to the economy?Additionally, they largely support the idea that raising taxes may raise government revenue, but typically at the expense of economic expansion and taxpayer mobility. On the other side, tax cuts often lead to short-term revenue losses while promoting long-term economic growth.
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vendor analysis is the examination of the _________ of purchased materials. a. function b. source c. quality d. cycle e. quantity sources
Answer:
B. source
Explanation:
Supplier analysis also involves examining the source of purchased materials, that is, where the materials used to produce the company's products or services come from. This may include analysis of factors such as the location of suppliers, the sustainability of their production practices, and the social and environmental impact of their operations.
A high average inventory value reduces the chances of inventory obsolescence.
a. True
b. False
False, A high average inventory value does not reduce the chances of inventory obsolescence.
An estimation of the worth or quantity of a certain commodity or group of goods over two or more specified time periods is known as average inventory. By averaging the beginning and ending inventory values throughout a certain time period, average inventory is the mean value of inventory during that time period, which may differ from the median value of the same data set. The value of all the products that are in stock and ready to be sold, as well as all the raw materials used to make those products, is known as inventory. Since it enables them to better manage their total business in terms of sales, costs, and relationships with their suppliers, successful inventory management is a crucial focus for businesses.
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on september 12, fang company sold merchandise of $5,800 to brown company, with credit terms of 2/10, n/30. the cost of the items sold is $4,000. fang uses the perpetual inventory system and the net method of accounting for sales. on september 14, brown returns some of the merchandise. the selling price of the merchandise is $500 and the cost of the merchandise returned is $350. brown pays the invoice on september 18 and takes the appropriate discount. the journal entry that fang makes on september 18 is:
Using the perpetual inventory system and the net method of accounting for sales, on September 18, the journal entry that Fang Company makes is as follows:
Journal Entry:Sept. 18:
Debit Cash $5,194
Credit Accounts Receivable (Brown Company) $5,194
(To record the receipt of cash on account from Brown.)
What is the perpetual inventory system?Under the perpetual inventory system, inventory transactions are recorded as they occur and not at the end of the financial period.
What is the net sales method?Under the net sales method, discounts are deducted when sales are recorded and not when payments are received with appropriate adjustments if there are sales returns and allowances.
On the other hand, the gross sales method does not deduct the sales discounts until payments are received.
Transaction Analysis:Sept. 12: Accounts Receivable (Brown Company) $5,684 Sales Discounts $116 Sales Revenue $5,800
Credit terms of 2/10, n/30
Cost of goods sold $4,000 Inventory $4,000
Sept. 14: Sales Returns $500 Accounts Receivable (Brown Company) $490 Sales Discounts $10
Inventory $350 Cost of goods sold $350
Sept. 18: Cash $5,194 Accounts Receivable (Brown Company) $5,194
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When real interest rates rise, consumption will shift: Group of answer choices downward if there is saving downward if income rises as well upward if the substitution effect outweighs the income effect upward if the income effect outweighs the substitution effect
When real interest rates rise, consumption will shift: downward if there is saving. Option A
What are real interest rates?Generally, If real interest rates rise, it typically means that the cost of borrowing money has increased.
This can lead to a reduction in consumption, as people may be less willing to take on debt to finance their purchases.
This effect is known as the substitution effect, as people substitute away from borrowing and towards saving. The income effect, on the other hand, refers to the impact that a change in income has on consumption.
If real interest rates rise and people save more as a result, their disposable income will also increase. This could lead to an increase in consumption, as people have more money to spend.
Ultimately, whether consumption shifts upward or downward will depend on whether the substitution effect or the income effect is stronger.
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The day-to-day operations of a corporation are overseen by a. the officers. O b. the owners. O c. the shareholders. d. the directors.
The day-to-day operations of a corporation are overseen by the officers. Hence, option (a) will be regarded as the relevant option choice.
Give a brief account on corporation.Unrelated to its owners, a corporation is a separate legal entity. Numerous legal rights and obligations apply to businesses just like they do to people. They have the authority to carry out a contract, lend as well as borrow money, bring on legal actions and defend them, choose judges, own property, and pay taxes. A Corporation can at times be regarded as a "legal person."
Some corporation conduct business both under their own names and under different trade names, such as Alphabet Inc., which is best known for operating as Goo-gle. Although the exact legal definition of a company varies from one state to the next, limited liability is usually the corporate form's most crucial feature. By receiving dividends and rising stock prices, shareholders can partake in the company's profits, but they are not personally responsible for the obligations of the business.
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What do subject-matter experts do to support data-driven decision-making?
SMEs are essential in helping to interpret the data and provide context and insights that can help inform decision-making.
Data-driven decision-making is becoming increasingly popular as organizations seek to make decisions that are based on evidence rather than guesswork. SMEs can provide the necessary expertise to identify trends and patterns in the data, as well as explain how these trends might affect the organization.
SMEs are also invaluable in helping to identify potential issues or red flags that may arise from the data. By using their expertise and knowledge, SMEs can help to identify any potential risks or problems that may need to be addressed.
In addition to interpreting data, SMEs can also guide how to best use the data to make decisions. They can help to evaluate different options and weigh their pros and cons, as well as provide advice on the best way to use the data for decision-making purposes.
In short, SMEs are essential to data-driven decision-making as they provide the necessary expertise and guidance to make informed decisions based on data. Without SMEs, data-driven decision-making would be impossible, leaving organizations to rely solely on guesswork and intuition.
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What are the price controls of the market?
Government regulations on wages, prices, or their rates of change are known as price controls. Such restrictions can be imposed by the government on a variety of products and services or, more frequently, on a market for a particular good.
The amount of money that an employer gives an employee for work that is finished within a particular amount of time is known as a wage. A few examples of wage payments include the minimum wage, going rate, annual bonuses, and compensatory benefits like prizes and tip money. Wages are included in the costs of running a firm. No matter how successful the company is, it has a responsibility to the employee. Payment by wage contrasts with salaried work, where the employer pays an agreed-upon sum at regular intervals (like once a week or once a month) regardless of the number of hours worked, commission-based pay, where pay is based on individual performance, and compensation based on the performance of the company as a whole. Employee perks, which are non-cash types of compensation, may also be given to wage earners in the form of tips or gratuities from clients. Since wage labour is the most common type of employment, the term "wage" is occasionally used to refer to all forms of employee pay, including monetary compensation.
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What are the three C in credit?
Character, Capacity and Capital
Those who someone may be looking into getting a loan from will assess the riskiness of lending to that individual based on these^ characteristics, and then decide whether or not to approve or deny the loan request.
Problem situation: alec buys tickets to an amusement park. He buys one adult ticket for $45 and four youth tickets. He pays a total of $137. What is the cost of a youth ticket? complete the equation to represent this situation. The letter t represents the cost of a youth ticket.
A child's ticket costs $23.00.
How do equations work?
a formula that demonstrates the equality of two mathematical expressions.
The young group is traveling to a theme park in a different region of the state. Each member of the group must pay $150 for the excursion, which covers two one-day combo entrance and meal passes and $85 for the accommodation.
a. Create an equation to represent the trip's cost. P should represent the park pass's price. Alec purchases amusement park tickets in light of this. He spends $45 on one adult ticket and $4 on four kid's tickets.
If each juvenile ticket costs c, then
137 = 45 + 4c 4c = 92 c = 23.
As a result, each child ticket is expensive.
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under which market conditions is there deadweight loss associated with the profit-maximizing output? check all that apply.
When supply and demand are out of equilibrium, a deadweight loss arises, which impairs the efficiency of the market. When items on the market are either overpriced or undervalued, market inefficiency results.
Deadweight loss is the market inefficiency brought on by over- or underproduction of products and services, which lowers the overall economic surplus. Deadweight losses may be brought on by taxation, monopolies, price floors, and price limits, among other things. By producing the amount where marginal income and marginal cost overlap, a monopolist maximises profit. As a result, society loses weight and there is a transfer of value from the consumer to the monopolist. Consumer surplus is much lower than it would be in a market with perfect competition because monopolistic companies set prices higher than marginal costs. Deadweight is lost as a result, and the economic surplus is reduced overall.
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Does the method for calculating credit scores seem fair to you? Why or why not?
Credit scores are primarily determined by your payment history, credit utilization, average age of your accounts, account mix, and frequency of credit applications (inquiries).
What is the method for calculating credit scores ?While each of these factors is significant, they are not all given the same weight by the hundreds of credit scoring models in use today.
Your financial situation does not always factor toward your credit score. Rent and utility payments are frequently not recorded to credit bureaus, so even if you have been making them on time for years, you may still not have a credit history. This might be particularly challenging for young people or newly arrived immigrants.
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if buyers believe that 50% of used refrigerators in the market are lemons (low quality), what fraction of used refrigerators sold will actually be lemons (low quality)?
Even when consumers do not have the time or expertise to assess the quality of products, they can make useful inferences about a product's quality from the length of its warranty.
What Is the Lemon Law for Refrigerators?
Under state or federal Lemon laws, you may be qualified to file a consumer claim. The intricacies of acquiring cars, trucks, and similar vehicles are directly tied to state lemon laws, which are present in all 50 states.
However, consumers who have suffered losses as a result of faulty dishwashers and refrigerators may still be able to file a lawsuit under the federal Magnuson-Moss Warranty Act.
One could claim that their warranty has been violated if they have attempted to repair their appliance multiple times during the guarantee's duration and are still dealing with downtime and other product issues.
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How can an individual shape public policy?
In contrast to other forms of governance, Western-style democracies are unique in how they formulate public policy.
What are the factors that shape the development of public policy?Through advocacy, education, or the mobilization of interest groups, individuals and organizations frequently try to influence public policy. Clearly, Western-style democracies differ from other types of government in how they shape public policy.
Public opinion, economic situations, new scientific discoveries, technical advancements, interest groups, non-governmental organizations (NGOs), commercial lobbying, and political action are just a few of the variables that have an impact on public policies.
By being knowledgeable about pertinent developments, circumstances, and actors, such as financial considerations, political considerations, and public opinion, you can exert influence. Your choice of definition for the issue will have an impact on whether and how policies need to be created or modified.
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What are 3 benefits of stocks?
Here are the 3 benefits of stocks:
The potential to earn higher returnsThe ability to earn regular passive incomeThe ability to protect our wealth from inflationWhat is stocks?In finance, stock consists of all the shares by which ownership of a corporation or company is divided. A single share represents a partial ownership of the company in proportion to the total number of shares. This usually gives stockholders a share of the company's profits, the proceeds of liquidation of assets or voting rights, usually divided among them in proportion to the amount each shareholder has invested. All shares are not necessarily equal, as certain classes of shares may be issued, such as non-voting, with enhanced or given voting rights to receive profits or liquidation before or after other types of shareholders.
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jimmy must be at work no later than 7:00 a.m. on the days he works. because he must hurry to get to work, he runs over a lady going across the street. she sues jimmy and his employer for her injuries. she has:
Jimmy has to be at work by 7am on working days. As he has to rush to work, he is run over by a woman crossing the street. She is suing Jimmy and his employer for injuries. she has a lawsuit against Jimmy, but not against his employer.
Can I sue my employer for workplace injury in California?Generally, you cannot sue your employer for work-related injuries, including those from slips and falls. Instead, you should apply for workers' compensation through the California Workers' Compensation System. In California, the statute of limitations for personal injury is usually two years from the date of injury.
How do you file a complaint against an employer in Florida?In most cases, you cannot sue your Florida employer for work-related injuries. However, there are some exceptions where you can sue your employer. There are two ways to complain to the DOL (Department of Labor). You can visit website at DOL to find the office closest to you, or call 1-866-4USWAGE to make a claim.
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the three dimensions of customer service are:group of answer choicesproduct quality, customer experience, and communication.diligence, communication, and customer experience.product quality, feedback, and service motivationmunication, resilience, and service motivationmunication, product quality, and diligence.
Diligence, communication, and client experience make up the three components of customer service.
What is communication and explain?Giving, receiving, & exchanging information are all parts of communication, which might take the form of talking, writing, listening, or reading. Good communicators pay close attention to others' opinions, talk or write effectively, and respect them. process when data is exchanged between people via a common set of signs, symbols, or actions.
Why is communication important?In daily life, communication enables us to relate to people, share our experiences and needs, and strengthen our bonds. It gives us the chance to communicate our views, share data, and express our emotions. All of us must communicate.
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In a paragraph response below, describe how the structure and organization of this text affected the listening/reading experience. How did it enhance the message behind the speech?
Text structure gives a text meaning since writers must arrange their work differently based on the type of information they're trying to convey. By comprehending and making use of the text structure while reading, readers can learn important facts and, as a result, the book's overall goal.
What is text structure?Text structures explain the organization of information in writers' texts. By comprehending the fundamental structure of texts, students may focus on key concepts and relationships, make predictions about what will occur next, and keep a record of their knowledge as they read.
A few examples of text structures are sequential, narrative, time, compare/contrast, proposition/support, problem/solution, order/chronology, cause/effect, inductive/deductive, and research.
The structure of academic writing must be sound. Academic writing requires a clear framework and logical flow in order to be coherent.
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Who do interest groups represent quizlet?
Before their government, interest organizations speak on behalf of the people. By identifying these issues, interest organizations effectively reflect the concerns of their members in the political process. Interest groups provide a forum for political participation.
How do interest groups function? They stand for what, exactly?In order to pursue shared political goals, individuals form groups known as interest groups. They often focus their efforts on one specific area of policy, in contrast to political parties, who must address every issue on the public agenda.
Who speaks on behalf of interest groups and what are their names?Professional lobbyists work to sway laws, regulations, or other governmental acts, decisions, or policies on behalf of an organization or individual who pays them.
What is an interest group's principal goal?An interest group's main goal is to sway public policies in favor of the group's members or their own interests. The general public and decision-makers are informed, among other things, about the problems that these organizations are attempting to solve.
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What movement of the government can help the inflation rate?
Contractionary financial strategy is presently a more famous technique for controlling expansion. By raising interest rates, a contractionary policy seeks to reduce an economy's money supply.
By making credit more expensive, consumers and businesses spend less, which slows economic growth.
What measures can the government take to lower inflation?In response to rising inflation, the Federal Reserve has raised interest rates to reduce demand for goods, services, and labor. Output and employment will decrease, price and money wage movements will slow, and core price inflation will eventually decrease if interest rates are raised sufficiently.
Which strategy contributes to inflation control?A contractionary monetary policy is one common method of managing inflation. Inflation can be controlled. A contractionary strategy means to decrease the stockpile of cash inside an economy by bringing down the costs of securities and increasing loan fees.
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