what is the effect of the abnormal protein on tissue function in duchenne muscular dystrophy and skeletal muscle tissue?

Answers

Answer 1

Answer:

Lack of the dystrophin protein in muscle cells causes them to be fragile and easily damaged. DMD carriers are females who have a normal dystrophin gene on one X chromosome and an abnormal dystrophin gene on the other X chromosome. Most carriers of DMD do not themselves have signs and symptoms of the disease, but a minority do. Symptoms can range from mild skeletal muscle weakness or cardiac involvement to severe weakness or cardiac effects and can begin in childhood or adulthood.

Explanation:


Related Questions

Question 1 of 5
What is one way water moves through the nonliving parts of an ecosystem
during the water cycle?
A. Transpiration
B. Evaporation
ОООО
C. Photosynthesis
D. Sweating

Answers

i think it is B
explanation: water droplets or anything comes from the ground and goes up in into the clouds to create evaporation which then fills the clouds to make it rain.

What would happen within a cell if it had a premature termination codon in the gene encoding the ER protein translocator?
A. There would be no transmembrane proteins found in any membranes in the cell B.Nonsense mediated decay (NMD) could interfere with translation of the mRNA encoding the ER protein translocator C. N-linked glycosylation on proteins usually translocated into the ER would not occur D. All of the above E B and C are correct

Answers

Nonsense-mediated decay (NMD) can easily interfere with the translation of the mRNA which is responsible for encoding the ER protein translocator. Therefore, option "B" is correct. The genetic code consists of three STOP codons or nonsense codons which are  UGA, UAG, and UAA.

These codons are frequently referred to as termination codons or nonsense codons. They do not encode any amino acid. Nonsense codon at the end of the polypeptide chain during translation is responsible for the end. Inserting a premature terminal codon (PTC) into a quality exon can code for incorrect mRNA, for example, cytoplasmic occasion.

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What was the purpose of the Multiple Use Sustainable Yield Act?

To create standard expectations for various types of land use

To require companies to find several uses for any land they occupy

To designate any land that is home to endangered species as protected

To make sure that all aspects of a land’s use are considered in its management

Answers

Answer:

On June 12, 1960, Congress passed the Multiple Use-Sustained Yield Act, designed to prevent the obliteration of national forests by logging and water reclamation projects.

Explanation:

Stage 2 (short term swim failure) occurs 3-30 minutes following immersion in cold water. What happens in Stage 2 if cold water immersion?

Answers

When cold water immersion occurs, in Stage 2 (short term swim failure) which takes place 3-30 minutes after immersion, the victim experiences the physiological changes such as hyperventilation,

which is rapid and deep breathing that exceeds the metabolic needs of the body, leading to carbon dioxide loss. It could lead to hypocapnia when there is an abnormally low level of carbon dioxide in the blood. Below are other physiological changes experienced during Stage 2 (short term swim failure):Lack of coordination Inability to carry out simple tasks such as swimming Muscle cramps Reduced core body temperature Cyanosis (the bluish discoloration of the skin and mucous membranes caused by inadequate oxygenation of the blood)

This results in the inability to swim or perform other tasks that involve the use of limbs. In more than 100 cases, the victim quickly loses consciousness and drowns.

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Final answer:

Stage 2 of short-term swim failure following immersion in cold water involves peripheral vasoconstriction, shivering, and cognitive impairment.

Explanation:

In stage 2 of short-term swim failure following immersion in cold water, several physiological changes occur. One significant change is the constriction of blood vessels in the arms and legs, known as peripheral vasoconstriction. This occurs as a result of the body's attempt to redirect blood flow to vital organs in order to maintain core body temperature.

In addition, during stage 2, shivering may begin as a way to generate heat and increase body temperature. Shivering helps the body to maintain its thermoregulation.

Finally, cognitive impairment can occur during stage 2. This includes difficulties with concentration, decision-making, and coordination, which can impact a person's ability to swim and increase the risk of drowning.

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Can someone help me with this one??


"Construct an explanation based on evidence for how the principles impact the

process of natural selection"

Answers

Answer:

The principles are responsible for the natural selection of organisms.

Explanation:

The principles greatly impact the  process of natural selection because these principles are responsible for the natural selection of organisms. If the organisms have all the principles of natural selection, it has more chances of survival as compared to other organisms due to the presence of the favourable characteristics. These favourable characteristics helps the organisms to increase in population because the environment is suitable for them or in other words the organisms can tolerate that environment better than other organisms. for example, polar bear survives in the polar regions because they have a thick skin full of hair that helps in the survival on the cold regions, it is an act of natural selection.

What are exons and introns and how are they dealt with in the cell?

Answers

Answer:

Exons are coding sections of an RNA transcript, or the DNA encoding it, that are translated into protein. Exons can be separated by intervening sections of DNA that do not code for proteins, known as introns.

Explanation:

The theory of evolution through natural selection is considered a scientific theory because _____. See Concept 22.3 (Page 475) The theory of evolution through natural selection is considered a scientific theory because _____. See Concept 22.3 (Page 475) it is broad enough in scope to explain many observations it is supported by a massive body of evidence from many disciplines it is general enough to provide many testable hypotheses All of the above are correct. None of the above is correct.

Answers

Answer:

All of the above are correct:

it is broad enough in scope to explain many observations it is supported by a massive body of evidence from many disciplines it is general enough to provide many testable hypotheses

Explanation:

The scientific theory is a conceptual framework used to explain facts or phenomena and to make predictions.

The theory is fundamental to science because it allows scientists to organize and understand observations.

The construction of a theory begins with a hypothesis. The scientist believes that a phenomenon occurs in a certain way, so he/she performs observations under the scientific method to prove that his/her hypothesis is valid or not valid. The systematization of the observations and the empirical data collected might derive from a scientific theory that explains the analyzed phenomenon.

A scientific theory is a knowledge that has been contrasted in several ways.

The theory of evolution has been tested in too many ways and by different disciplines, becoming one of the most strong theories. Research areas such as biology, genetics, paleontology, and geology, among others, have been tasting it and explaining many facts from it, which makes it broad enough to base on it any explanation of life.

pls answer soon 8th grade science

Answers

Answer: 1. Is true 2. is false 3. Is true 4 is true 5. Is false 6. Is true 7. Is false 8. Is true 9. Is true 10 is false 11. Is false

I couldn’t answer so I just commented the answers to part 1

Part b. 12. B, 13. E, 14. A, 15. D, 16. C.

now I did as a actua answer

Explanation:

XBXь х Хү
What is the probability that this couple will have a colorblind son?

Answers

Answer:

2

Explanation:

Which compliment pathway involves binding of compliment to the lipopolysaccharide layer of the bacterial cell wall?
a) Classic Pathway
b) Mannose-binding Lectin Pathway
c) Alternative Pathway

Answers

The complement pathway that involves binding of complement to the lipopolysaccharide layer of the bacterial cell wall is: Alternative Pathway. (Option c)

The alternative pathway is one of the three main complement activation pathways, alongside the classical pathway and the lectin pathway. It is called the alternative pathway because it can be initiated directly without the need for specific antibody-antigen complexes.

In the alternative pathway, complement proteins, such as C3, can spontaneously and continuously undergo low-level activation in the bloodstream. This activation occurs when complement proteins interact with certain molecules present on the surface of microorganisms, including the lipopolysaccharide (LPS) layer of bacterial cell walls.

The binding of complement proteins to the LPS layer triggers a cascade of enzymatic reactions, leading to the generation of complement fragments, such as C3b. These fragments can then bind to the bacterial surface, promoting opsonization (marking bacteria for phagocytosis), triggering inflammation, and ultimately leading to the destruction of the bacterial cells.

Therefore, the correct answer is c) Alternative Pathway.

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The apical and basal surfaces are the 2 sides of all connective tissues.
A. True
B. False

Answers

The answer to this question is true

Water is a product of cellular respiration. True or False

Answers

Answer:

true

Explanation:

During aerobic cellular respiration, glucose reacts with oxygen, forming ATP that can be used by the cell. Carbon dioxide and water are created as byproducts. Water and carbon dioxide are released as byproducts.

question 88 91) how is natural selection related to sexual reproduction as opposed to asexual reproduction? a) sexual reproduction results in many new gene combinations, some of which will lead to differential reproduction. b) sexual reproduction results in the most appropriate and healthiest balance of two sexes in a population. c) sexual reproduction results in the greatest number of new mutations. d) sexual reproduction allows the greatest number of offspring to be produced.

Answers

Natural selection related to sexual reproduction as opposed to asexual reproduction: sexual reproduction results in many new gene combinations, some of which will lead to differential reproduction. The correct option is a.

How does sexual reproduction influence natural selection?

The differentiating force of natural selection is influenced by sexual reproduction. Reproduction that is asexual produces offspring that are genetically identical to their parent. This means that all descendants inherit all of their parents' genetic material. In comparison to asexual reproduction, sexual reproduction produces offspring that contain a mixture of genetic material from both parents.

This makes each new individual genetically different from both its parents and other members of the population. This increases the possibility that some individuals would be better adapted to their environment than others. The offspring inherit a combination of genes from both parents, resulting in a greater variation in the population.

This variation may lead to the survival of some individuals with genetic adaptations that enable them to cope with changes in their environment, while others with unsuitable genetic adaptations would not be able to cope. In conclusion, natural selection is influenced by sexual reproduction because it results in many new gene combinations, some of which will lead to differential reproduction. The correct option is a.

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Where doed fertilisation take place?

Answers

Answer:

please give me brainlist and follow

Explanation:

fallopian tube

Fertilization usually takes place in a fallopian tube that links an ovary to the uterus. If the fertilized egg successfully travels down the fallopian tube and implants in the uterus, an embryo starts growing.

Which planets have interiors made of partially frozen water and ammonia?​

Answers

The answer is Uranus and Neptune

Pls help and thank me

Answers

I think the answer is b

As soil particle size decreases, capillary action will​

Answers

Answer:

Increases

Explanation:

The smaller is the size of the soil, the greater is the interspace distance between the two soil particles. As this distance increases, the water gets more space to travel through thereby increasing the capillary action. Hence, as the size of soil particle reduces, capillarity increases.

Which of these molecules would form a single covalent bond?





Group of answer choices

Na3N


NaCl

KCl

Cl2

Answers

Answer: Cl2

Explanation:

Which of the following is an example of a private effort to help the environment? *
A. An individual donates money for a park.
B. A business recycles its waste.
C. A nonprofit group buys land for preservation.
D. all of the above

Answers

Answer:

The correct answer is - D. all of the above.

Explanation:

Any effort from a private sector made for the preserve or help for the betterment of the environment and ecology. Establishing and making a park will help in increasing plant diversity which increases the air quality of the ecosystem and atmosphere.

An individual donates money for the park. Recycling the waste of a private business is also hep in maintaining the environment. Preserving the land also helps the environment.

What are the characteristics of iodine ?

Answers

Iodine is a non-metallic, dark-gray/purple-black, lustrous, solid element.

Drag each tile to the correct box.

The specific heat of three substances in the image are given in the table.


stamped concrete - 0.75
grass-covered soil - 1.01
Water - 4.18

Place the areas in order based on how fast they’ll heat up on a sunny afternoon. Start with the fastest and end with the slowest.


PLEASE ANSWER QUICKLY I WILL GIVE BRAINLIEST!!

Answers

Answer:

Correct answer is A-C-B

Explanation:

Just took the test

The concrete has the lowest specific heat, so it requires very little heat to heat up, making it the fastest substance to heat up; the second is grass, and the third is water, which requires a high temperature to heat up, so A-C-B is the correct order.

What is the significance of the specific heat of the substances?

Specific heat is explained as the amount of heat that is needed to raise the temperature by 1 degree, and here the water needs the highest temperature to raise the temperature by 1 degree as a result, even if the water gets a little bit more temperature, it will not be too hot right away.

Hence, the concrete has the lowest specific heat, so it requires very little heat to heat up, making it the fastest substance to heat up; the second is grass, and the third is water, which requires a high temperature to heat up, so A-C-B is the correct order.

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suggest reasons why missplicing errors may result in cf. be specific and refer to what you have learned about dna mutations and protein synthesis in the cell.

Answers

"Cystic fibrosis (CF) is a genetic disorder caused by mutations in the CFTR gene. This gene provides instructions for the production of a protein that is responsible for the regulation of ion transport in cells."

Missplicing errors may result in CF for the following reasons:DNA mutations Mutations are changes that occur in the genetic material of an organism, DNA, which can affect how proteins are synthesized in the cell. Mutations in the CFTR gene can lead to the production of an abnormal protein or to the absence of the protein, which can cause CF.Protein synthesisMissplicing errors occur when the introns, non-coding regions, of a gene are not removed properly, leading to the production of an abnormal protein. In the case of CF, the missplicing of the CFTR gene can result in a protein that is not functional, leading to the symptoms of CF. Therefore, missplicing errors can cause CF by disrupting the normal protein synthesis process, resulting in an abnormal protein that does not function properly.

Cystic fibrosis (CF) is a genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The CFTR gene provides instructions for producing a protein that is responsible for maintaining the balance of salt and water in various organs, including the lungs, pancreas, and digestive system.

There are more than 1,700 different mutations identified in the CFTR gene that can cause cystic fibrosis. The most common mutation is known as ΔF508 (Delta F508), which accounts for approximately 70% of CF cases in individuals of European descent. This mutation involves a deletion of three nucleotides in the CFTR gene, resulting in the loss of a phenylalanine amino acid at position 508 of the CFTR protein.

The ΔF508 mutation leads to a defective CFTR protein that is misfolded and degraded before it reaches the cell surface. As a result, chloride ions are unable to move through the CFTR channel properly, disrupting the normal flow of salt and water across cell membranes. This disturbance affects the function of various organs, particularly the respiratory and digestive systems.

Other less common CFTR gene mutations can also cause cystic fibrosis, and the specific mutation a person carries can affect the severity and progression of the disease. Genetic testing is used to identify CFTR gene mutations in individuals suspected of having cystic fibrosis or as a part of carrier screening to assess the risk of passing on the condition to future children.

It's important to note that advances in genetic research and personalized medicine continue to expand our understanding of cystic fibrosis and the role of different mutations in the disease. New therapies and treatments are being developed to target specific genetic mutations and improve outcomes for individuals with cystic fibrosis.

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Explain the mistake you see in image 1

Answers

Answer:

There is no image

Explanation:

Try and upload it

Question 29 (2 points) Listen Recent, newer discoveries of oil resources tend to have which characteristics? They are deeper, farther, more expensive, and more dangerous to access and extract. They are cheaper, closer, cheaper, and safer to access and extract. They are in locations that would not be harmed if a spill were to occur. None of the above

Answers

Recent, newer discoveries of oil resources tend to have the characteristic of being cheaper, closer, cheaper, and safer to access and extract. These resources are discovered through the exploration and drilling of new oil fields.

Explorers are always searching for new and it is difficult to determine the exact location of a deposit until it has been discovered. Recent, newer discoveries of oil resources have been found to be less expensive and easier to extract than oil from older, established fields. This is due to advances in technology and the development of new drilling techniques.

In addition, newer oil fields tend to be closer to population centers, making it easier to transport the oil to refineries and processing plants. They are also often located in areas that are less environmentally sensitive, reducing the risk of spills and other environmental damage.

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need help please!!!!!!!

Answers

Answer:

...

Explanation:

The behavior of an organism is influenced by both internal and external factors. How might a bear be influenced by external factors in its environment? A. A decrease in the number of fish causes bears to start consuming more plants. B. An increase in hunting causes bears to stay in covered areas and avoid humans. C. A decrease in temperature causes bears to look for food during the day instead of at night. D. all of these

Answers

Answer:

D. all of these

Explanation:

I just got it right in study island (:

Answer:

it's D

Explanation:

Which moon phase is represented in the diagram below?*

new
first
full
waning crescent

Answers

Answer:waning cresent

Explanation:waning crescent

Produces and secretes bile. Alternates contraction and relaxation of smooth muscles along the length of the GI tract. Largest salivary gland anterior to each ear. Another term for chewing. Covers dentin and glues the teeth to the periodontal ligament. Secrete hydrochloric acid in the stomach. Vessels absorbing and transporting fatty acids and monoglycerides. Pancreatic juice enters this region of the small intestine. Has both endocrine and exocrine functions. Finger-like extensions in the epithelial cell membrane.

Answers

Answer:

The correct answer would be -

1. liver 2. peristasis 3. parotid 4. mastication 5. cemuntum 6. parietal cell 7. Lacteal 8. duodenum 9. Pancreas 10. microvilli

Explanation:

The liver is the gland or the organ that is responsible for the production of bile and secreted into the duodenum during digestion.

Peristalsis is the movement that helps in forwarding propulsion of food/bolus

The parotid is a gland that produces and secrets saliva for moistening the food and digesting carbohydrates.

Mastication is a process that helps in crushing and breaking the food into smaller pieces.

Cementum is a substance that covers the root of the teeth and glues the teeth to the periodontal ligament.

Parietal cells secrete hydrochloric acid to remove the pathogens and activating pepsinogen.

Lacteal vessels absorb fatty acids and transport them

Duodenum is the region where pancreatic juice and bile is secreted.

The pancreas is an organ and gland that acts as exocrine and endocrine gland

Microvilli are the projection look like fingers in the epithelial cell membrane.

Explain how the interaction of the Sun, the atmosphere, and the oceans produce winds.

Answers

Answer:

The heating of the Earth's surface and atmosphere by the sun drives convection within the atmosphere and ocean. This convection produces winds and ocean currents. The greater the pressure differences between a low-pressure area and a high-pressure area, the stronger the winds.

Explanation:

The heating of the Earth’s surface and atmosphere by the sun drives convection within the atmosphere and ocean. This convection produces winds and ocean currents. The greater the pressure differences between a low-pressure area and a high-pressure area, the stronger the winds.

A student remarks that it is a good thing that humans discovered how to use industrial processes to fix nitrogen because this ensures that the nitrogen cycle can remain intact if nitrogen-fixing bacteria ever go extinct. Evaluate the accuracy of this statement. A. The statement is accurate because humans are able to fix nitrogen on a large scale that rivals the rate of the process carried out by bacteria. B. The statement is inaccurate because the nitrogen cycle does not depend on nitrogen-fixing bacteria, and their loss would not cause a problem. C. The statement is inaccurate because the product of nitrogen fixation through industrial processes does not have the same biological properties as the product of nitrogen fixation by bacteria. D. The statement is inaccurate because humans would not be able to distribute the product of nitrogen fixation from industrial processes in the same way that bacteria are able to distribute it globally now.

Answers

Answer:

D. The statement is inaccurate because humans would not be able to distribute the product of nitrogen fixation from industrial processes in the same way that bacteria are able to distribute it globally now.

Explanation:

Nitrogen fixing bacteria has the responsibility in nature to trap and fix atmospheric nitrogen in ecosystems. They are very important components of the nitrogen cycle and play an important role in maintaining the balance  of nutrients in nature.

If humans discover industrial processes to fix nitrogen, the process will be unsustainable in the long run if nitrogen-fixing bacteria ever go extinct because humans would not be able to distribute the product of nitrogen fixation from industrial processes in the same way that bacteria are able to distribute it globally now across several ecosystems all over the world.

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Let f be a function defined on all of R, and assume there is a constant c such that 0 determine the number of moles of air present in 1.35 l at 750 torr and 17.0c. ideal gas law formula: pv = nrt(r = 62.396 ltorr/molk) which equation should you use? "Disuss function of management and the managemnt roles, important to the strategies partnership between GEELEY AND PROTON WITH EXAMPLE EACH." Predicate Logic ..... 14 marks In the following question, use the following predicates about beings eating different type of food: 1. E(x,y): 2 eats y 2. D(2): x is a donkey 3. C(x): is a carrot 4. H(*): x is hungry (a) (3 marks) Give all correct logic translations of the English sentence "Some donkey is hungry." A. Vz(D() + H(2)) B. 3x(D(x)) + H(x) C. Vx(D(2) A Hz)) D. Vx(D(x) V H()) E. 3x(D(2) A H(2) F. 3x(D(x) V H:)) G. -Vx(D(x) +-H(2)) H. None of the above. (b) (3 marks) Give all correct English translations of the formula Vr(EyE(,y) + 3z(E(2, 2) AC(z))). A. The only thing eaten are carrots. B. Everything that is hungry eats carrots. C. Everything that eats something must eat some carrot. D. Every donkey eats some carrot. E. Hungry donkeys eat some carrots. F. If something eats carrots, then it eats everything. G. If something eats everything, then it must eat carrots. H. None of the above. humans have, and have had in the past, great influence on the biological diversity in their surrounding environment as a result of: a. determine the number of electrons in a system of cyclic conjugation (zero if no cyclic conjugation). Given the following demand data,PeriodDemand155251358452561a. Compute a weighted average forecast using a weight of 0.4 for the most recent period, 0.3 for the next most recent, 0.2 for the next, and 0.1 for the next. (Round all your answers to two decimal points.) of the 8 disorders discussed, which is the only one that is caused by a missing piece of a chromosome, not an entire missing or extra chromosome? Suppose you purchase the July 2020 call option on corn futures with a strike price of $3.30. Assume you purchased the option at the last price of the day. Use Table 23.2. a. 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The fair value and share price flow per option unit of Company A are as follows: However, it is assumed that the share price on December 31 and the stock price on January 1 of the following year are the same.Sun ChairFair Value of Options1 share price per weekJanuary 1, 201400200201-12-31500400December 31, 202600600December 31, 203700800(Question 1) When Company A decides to grant shares, seek compensation costs to be recognized in 202 and 203.(Question 2) When Company A decides to pay the difference between the compensation base price and the exercise price in cash, seek compensation costs to be recognized in the years 203 and 204, provided that the stock compensation cost is the conversion effect.(Question 3) This is an independent case from the above question. Company B granted 1,000 stock options to the Chief Executive Officer on January 1, 201, as a condition of providing 3 years of service. 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The company expected to use 7,400 direct labor hours per month except during July, August, and September when the company expected 9,100 hours of direct labor each month to build inventories for high demand that normally occurs during the Christmas season. The company's actual direct labor hours were the same as the estimated hours. The company made 3,700 units of product in each month except July, August, and September, in which it produced 4,550 units each month. Direct labor costs were $25.00 per unit, and direct materials costs were $11.60 per unit. Required a. Calculate a predetermined overhead rate based on direct labor hours. b. Determine the total allocated overhead cost for January, March, and August. c. Determine the cost per unit of product for January, March, and August. d. Determine the selling price for the product, assuming that the company desires to earn a gross margin of $20.80 per unit. Complete this question by entering your answers in the tabs below. 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Show less A January March August: Total allocated overhead cost Cost per unit Selling price per unit A certain transverse wave is described by the following equation.y(x, t) =(6.30 mm) cos2(x/31.0 cm -t/0.0320 s)(a) Determine the wave's amplitude.1mm(b) Determine the wave's wavelength.2cm(c) Determine the wave's frequency.3Hz(d) Determine the wave's speed of propagation.4m/s(e) Determine the wave's direction of propagation.+x -x +y -y